Discovery of a new tumor suppressor previously thought to be an oncogene

A gene that has for decades been considered a tumor promoter, the PLK1 gene, can also perform the exact opposite function: halting the development of cancer. The role of PLK1 as a target for powerful drugs must now be reviewed. For the time being, the scientists have discovered that the expression of PLK1 in breast tumors can determine a different prognosis, depending on the tumor sub-type.

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